Children’s Research Triangle’s (CRT) Trauma Treatment Program (TTP) was an assessment-driven, trauma informed intervention program based in Chicago, Illinois. Funded from 2009-2021 as a Community Treatment and Service Center for the National Child Traumatic Stress Network, the TTP made trauma-informed therapeutic services available to children and adolescents ages 0 to 18 by providing and evaluating evidence-based interventions, and educating professionals, caretakers, and other community members about the impact of trauma on youth. The TTP was an expansion of the existing program at CRT, thereby increasing the number of children served in the community. The TTP followed a comprehensive screening, assessment, and treatment process, which included foundational material from the NCTSN’s 2012 Breakthrough Series Collaborative, Improving Comprehensive Assessments and Case Formulations by Implementing the NCTSN Core Curriculum. As part of the TTP, all children and adolescents referred to CRT for services underwent an initial screening for trauma exposure. Children identified as having a history of trauma were referred for an assessment designed to obtain more information about the child’s trauma history, behavioral presentation, and trauma-related symptomatology. A high standard of care was ensured by ongoing training, consultation, and reflective supervision for TTP staff and partner sites. The TTP worked in multiple under-resourced community settings, requiring the use of a variety of treatment interventions to best meet the needs of the clients served. Consequently, the TTP employed several Evidence-Based Practices, including Child-Parent Psychotherapy (CPP), Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), and Structured Psychotherapy for Adolescents Responding to Chronic Stress (SPARCS). During each of the five years of funding, 400 children and adolescents were screened for traumatic histories; 225 underwent a systematic trauma assessment; 60 participated in TTP trauma-focused interventions; 60 participated in Youth Trauma Workshops; one partner agency received intensive consultation services; 100 community members received training about the mental health impact of childhood trauma, and 50 community members received training on prevention/mental health promotion topics related to childhood trauma. Taking into account overlap in screening, assessment, and treatment, CRT provided direct services to a minimum of 8,220 individuals over the twelve years. We are pleased that this grant also allowed us to expand services to military families in the Chicagoland area.